Fungal Argonaute proteins act in bidirectional cross-kingdom RNA interference during plant infection-Reference-Cited by-同舟云学术

Fungal Argonaute proteins act in bidirectional cross-kingdom RNA interference during plant infection

Published:2024-04-16 Issue: Volume: Page:
ISSN:
Container-title:
language:
Short-container-title:

Author:

Weiberg Arne¹^ORCID,Cheng An-Po¹^ORCID,Huang Lihong¹,Oberkofler Lorenz¹,Johnson Nathan R²,Salinas Francisco¹,Wange Lucas³^ORCID,Enard Wolfgang⁴^ORCID,Glodeanu Stefan-Adrian¹,Stillman Kyra¹

Affiliation:

1. Ludwig-Maximilians University of Munich (LMU)

2. Universidad Mayor, Santiago, Chile

3. Ludwig-Maximilians Universitaet, Munich

4. Ludwig-Maximilians University

Abstract

Argonaute (AGO) proteins bind to small RNAs to induce RNA interference (RNAi), a conserved gene regulatory mechanism in animal, plant, and fungal kingdoms. Small RNAs of the fungal plant pathogen Botrytis cinerea were previously shown to translocate into plant cells and bound to the host AGO, which induced cross-kingdom RNAi to promote infection. However, the role of pathogen AGOs during host infection stayed elusive. In this study, we revealed that members of fungal plant pathogen Botrytis cinerea BcAGO family contribute to plant infection and act in bidirectional cross-kingdom RNAi, from fungus to plant and vice versa. Providing these new mechanistic insights of pathogen AGOs promise to improve RNAi-based crop protection strategies.

Publisher

Springer Science and Business Media LLC

Reference67 articles.

1. Argonaute proteins: functional insights and emerging roles;Meister G;Nat Rev Genet,2013

2. RNA interference;Hannon GJ;Nature,2002

3. RNA interference pathways in fungi: mechanisms and functions;Chang SS;Annu Rev Microbiol,2012

4. Quelling: post-transcriptional gene silencing guided by small RNAs in Neurospora crassa;Fulci V;Curr Opin Microbiol,2007

5. Sixteen Years of Meiotic Silencing by Unpaired DNA;Hammond TM;Adv Genet,2017