Staphylococcus aureus pneumonia complicated with lower limb gangrene secondary to influenza A virus：a case report

Abstract

Abstract Background Millions of people worldwide die from lower respiratory tract infections every year, and a significant portion of these deaths can be attributed to seasonal influenza virus infections, due to the continuous emergence of new variants of influenza A virus (IAV) and secondary bacterialinfection with other viruses or bacteria. This report describes a female patient with IAV who secondary bacterial infection with Staphylococcus aureus and lower limb gangrene. Case presentation The patient was a 39-year-old female who had persistent cough, sputum and tight breath for 2 days, worsening for 11+hours. She received VV-ECMO treatment for severe pneumonia. Her alveolar lavage fluid showed Staphylococcus aureus, Influenza A virus was positive for H3N2. After anti infection treatment, the patient's condition improved, and gangrene occurred in the lower limbs and amputation surgery was performed. Conclusions Subsequent aureus infections after influenza can exacerbate respiratory failure in patients, leading to multiple organ dysfunction and even endangering patient safety. Early identification, identification of pathogens, and effective anti-infection treatment can improve prognosis.