Affiliation:
1. Regional School of Public Health, Catholic University of Bukavu
2. Competence Center for Methodology and Statistics, Luxembourg Institute of Health
3. Université Libre de Bruxelles
Abstract
Abstract
Purpose
The aim of this study was to identify the factors associated with long-term mortality in subjects treated for SAM in childhood 11 to 30 years after nutritional rehabilitation.
Methodology
Referring to the data collected from December 2017 to November 2018 from the Lwiro cohort; we updated this database with additional data. Records of subjects admitted for SAM between 1988 and 2007 were extracted from the archives of the pediatric hospital in Lwiro, South Kivu, Democratic Republic of Congo (DRC). A multivariate Cox proportional hazards regression was used to identify factors associated with long-term mortality.
Results
A total of 816 subjects were found to be alive and 119 died. The mean age at admission to nutritional rehabilitation was 46 months. Around two third of the subjects had edema, and in 6,8% of these subjects, edema had subsided after thirty days in hospital. Almost one in ten (9.5%) cases of SAM resulted in treatment failure. The risk of death was significantly higher in subjects with a history of therapeutic failure (hospital stay ≥ 45 days) and in those whose edema had melted late (≥ 30 days) during their hospitalization, with respective risks of HR = 1.98 (1.07; 3.67) and 2.81 (1.12; 7.03) respectively.
Conclusion
Good follow-up after hospital discharge is imperative to ensure the success of SAM management in the medium and long term. However, this follow-up must be more intensive in patients who have failed treatment and whose edema has melted late during hospitalization.
Publisher
Research Square Platform LLC
Reference40 articles.
1. World Health Organization, United Nations Children’s Fund (UNICEF)., International Bank for Reconstruction and Development/The World Bank. Levels and trends in child malnutrition: UNICEF/WHO/The World Bank Group joint child malnutrition estimates: key findings of the 2023. mai 2023.
2. Global, regional, and national prevalence of overweight and obesity in children and adults during 1980–2013: a systematic analysis for the Global Burden of Disease Study 2013;Ng M;Lancet Lond Engl 30 août,2014
3. The double burden household in sub-Saharan Africa: maternal overweight and obesity and childhood undernutrition from the year 2000: results from World Health Organization Data (WHO) and Demographic Health Surveys (DHS);Wojcicki JM;BMC Public Health 31 oct,2014
4. FAO. Appercu régional de la sécurité alimentaire et de la nutrition en Afrique. Gabon: Libreville; 2019.
5. Objectifs du Millénaire pour le développement (OMD). [Internet]. [cité 15 juill 2021]. Disponible sur: https://www.un.org/fr/millenniumgoals/reports/2015/index.shtml.