Prevalence of Respiratory Failure And Associated Factors In Adult Intensive Care Unit of Saint Paul’s And Addis Ababa Burn, Emergency And Trauma Hospital, Ethiopia 2020

Abstract

Abstract Background: Severe respiratory failure is a common reason for admission to the intensive care unit that occurs for several reasons, including pulmonary disease, neuromuscular disease, shock and the necessity for airway protection or temporary breathing support after major surgery. For patients with ARF, mechanical aeration is the cornerstone of management. Objective: to assess the prevalence of respiratory failure and associated factors among patients admitted the adult intensive care unit of Saint Paul’s Millennium Medical College and Addis Ababa Burn, Emergency and Trauma hospitals Addis Ababa, Ethiopia, 2020. Method: An institution based retrospective cross-sectional study was conducted from August 26 to September 25, 2020. Among a total of 2198 population, 384 samples were selected using systematic random sampling. A multivariable logistic regression analysis was used to identify predictors of respiratory failure using odds ratio, 95% confidence interval, and p-value < 0.05 to be considered as significant. Result: The prevalence of respiratory failure in this study was 139(36.2%).The variables which were significantly associated with respiratory failure were, patients age >50 (AOR =4.88(95%CI: 2.1, 11.4),Duration of stay at intensive care unit >15 days (AOR=0.24(95%CI: 0.086, 0.65), prolonged obstructive pulmonary disease (AOR=2.3 (95%CI: 1.98, 4.79),Asthma (AOR=0.23(95%CI: 0.087, 0.6) , sepsis (AOR= 0.43 (95% CI:0.2,0.94) , cardiac disease (AOR= 3.01(95%CI: 1.36, 6.66)), Human Immune Deficiency Virus (AOR=4.3(95%CI: 1.34, 13.92) and trauma (AOR= 2.93(95%CI: 1.36, 6.35). Conclusion: The prevalence of respiratory failure was high. Multiple factors influence the development of respiratory failure. Older age, cardiac disease, Human Immune Deficiency Virus and trauma were at risk of developed respiratory failure Therefore, Health care professionals, policy makers and other concerned bodies should give emphasis to the factors that contribute to the development of respiratory failure. They should give priority especially for older, HIV, cardiac, and trauma patients to provide easily accessible and quality care.