Affiliation:
1. Changchun University of Chinese Medicine
2. The Affiliated Hospital to Changchun University of Chinese Medicine
Abstract
Abstract
Background
This study aims to elucidate the association between glycemia and the occurrence of multi-vessel lesions in participants undergoing Percutaneous Coronary Intervention (PCI).
Methods
A cohort of 2,533 patients with coronary heart disease, treated with drug-eluting stents, was analysed. Of these, 1,973 patients, identified by the endpoint of multi-vessel lesions, were examined using univariate and multivariate logistic regression analyses to determine the relationship between glycemia levels and multi-vessel lesion occurrence.
Results
The analysis included 1,973 participants, among whom 474 patients were identified with coronary multi-vessel lesions. Univariate logistic regression analysis demonstrated a positive correlation between glycemia and the occurrence of coronary multi-vessel lesions (OR 1.04; 95% CI 1.01–1.08; p = 0.02)..The adjusted model indicated that for each unit increase in glycemia, the risk of developing coronary multi-vessel lesions increased by 4%, showing a significant correlation (p < 0.05). Subgroup analyses revealed that the impact of glycemia on multi-vessel lesions in patients with PCI varied according to gender, age, and smoking status, with the effect being more pronounced in men, older patients, and smokers。
Conclusion
Our findings establish a significant association between glycemia and the incidence of multi-vessel lesions, particularly pronounced in male patients, individuals over 45, and smokers.
Publisher
Research Square Platform LLC