Abstract
Abstract
Aim
The association of cardiac implantable electronic devices (CIED), namely pacemaker (PM), implantable cardioverter-defibrillator (ICD) and cardiac resynchronization therapy with (CRT-D) or without defibrillator (CRT-P), on health-related quality of life (HRQoL) is lacking.
Methods and results
Data from the Swedish Pacemaker and ICD Registry together with the European Quality of Life-5 Dimension questionnaire (EQ-5D) administered before and after one year the CIED implant from January 2019 to February 2022 were used to analyze the HRQoL with the EQ-5D visual analogue scale (EQ-VAS) and the EQ-5D index.
Of 1,479 who completed the EQ-5D, 80% had a PM, 10% an ICD, 5% a CRT-P and 6% a CRT-D. The median age was 77 years with a prevalence of females ranging from 38% in the PM group to 17% in the ICD group. The EQ-VAS and the EQ-5D index significantly increased in patients with PM and CRT-P (EQ-VAS +2.8, standard deviations (SD) 23 and +5.8, SD 24.9; EQ-5D index +0.019, SD 0.114 and +0.051, SD 0.125) while only the EQ-5D index increased in patients with ICD (+0.002, SD 0.104 ). After adjusting for age, sex and HRQoL at baseline, the presence of defibrillator was associated with lower EQ-VAS (-3.4, 95% confidence intervals (CI) -6.7; -0.1 and -4.8, 95% CI -8.8;-0.7) and EQ-5D index (-0.018, 95% CI -0.035; -0.0003 and -0.025 95% CI 0.046;0.004) at follow-up compared to PM.
Conclusion
These findings, showing the HRQoL associated with CIED, are important to support physicians' and pacemaker nurses' care after device implantation by embracing the patients’ perspectives.
Publisher
Research Square Platform LLC
Reference25 articles.
1. Patients’ knowledge and attitudes regarding living with implantable electronic devices: results of a multicentre, multinational patient survey conducted by the European Heart Rhythm Association;Haugaa KH;EP Eur,2018
2. The Impact of Cardiac Devices on Patients’ Quality of Life-A Systematic Review and Meta-Analysis;Willy K;J Cardiovasc Dev Dis,2022
3. Cardiac resynchronization therapy (CRT): Clinical trials, guidelines, and target populations;Linde C;Heart Rhythm,2012
4. Patient Perceptions and Quality of Life in Pacemaker Recipients;Polikandrioti M;J Innov Card Rhythm Manag,2021
5. Benefits of Participation in Clinical Trials: An Umbrella Review;Bouzalmate-Hajjaj A;Int J Environ Res Public Health,2022