Ultrasonographic endometrial classification in In Vitro Fertilization: a new approach

Abstract

In the context of In Vitro Fertilization (IVF), we introduce an innovative approach for assessing the endometrium via transvaginal ultrasound. Diverging from previous studies that centered on the comprehensive thickness and pattern of the endometrium, our methodology scrutinizes both the absolute and relative dimensions of its external layers, relative to the aforementioned factors. Our findings reveal a significant departure from conventional paradigms. Specifically, when the external layers of the endometrium achieve or exceed 50% of the total endometrial composition in a trilaminar configuration, a substantial enhancement in pregnancy rates is manifest. Conversely, when the proportion of external layers diminishes below 50% of endometrial thickness, a marked decline in pregnancy rates is evident. Furthermore, within both fresh and frozen embryo transfer cycles, the presence of slender external layers corresponds to a notable absence of pregnancies. Importantly, our study underscores that pregnancies did not occur when the total endometrial thickness measured below 7mm. The results gleaned from our comprehensive analysis, encompassing a cohort of 271 subjects, warrant replication and validation by fellow experts in the field. By corroborating these outcomes and embracing the novel classification of endometrial dynamics in IVF, clinicians and scientists can refine and optimize patient care in assisted reproductive technologies.