RELATİONSHİP BETWEEN ANDROGENETİC ALOPECİA AND CARDİOVASCULAR COMORBİDİTY MARKERS İN WOMEN

Abstract

Background Although androgenetic alopecia is a cosmetic problem for lots of men and women, it’s also investigated about relations with systemic diseases. Severity of androgenetic alopecia was found related to coronary artery diseases in some groups. Methods Twenty seven female volunteers with androgenetic alopecia older 18 years old were enrolled to the study. Androgenetic alopecia were scored by Ludwig classification. Blood biochemical markers which are related to cardiac diseases were studied. These were serum total cholesterol, high-density lipoprotein, low-density lipoprotein, triglycerides, dehydroepiandrosterone sulphate,total testosterone, C reactive protein levels. As imaging carotid ultrasonography was used. Right and left common carotid arteries’ intima media thickness were measured. Results No corelation with other serum low-density lipoprotein, total chlolesterol , triglyserides , C reactive protein and androgenetic alopecia severity could be found. A negative corelation between serum high-density lipoprotein level and Ludwig severity was investigated. Conclusions Patients of androgenetic alopecia must be also concerned about cardiac diseases. Measurement of carotid arteries’ intima media thickness in people with androgenetic alopecia measurement can be helpful in determining risk of premature cardiovascular heart diseases. There is a need for more clinical studies of relationship between serum lipids especially high-density lipoprotein and androgenetic alopecia severity in women. Keywords: female type androgenetic alopecia, DHEA-S, carotid intima media thickness, cardiovascular heart diseases,HDL