Polycomb/Trithorax response elements and epigenetic memory of cell identity-Reference-Cited by-同舟云学术

Polycomb/Trithorax response elements and epigenetic memory of cell identity

Published:2007-01-15 Issue:2 Volume:134 Page:223-232
ISSN:1477-9129
Container-title:Development
language:en
Short-container-title:

Author:

Ringrose Leonie¹,Paro Renato²

Affiliation:

1. IMBA - Institute of Molecular Biotechnology GmbH, Dr Bohr-Gasse 3, 1030 Vienna, Austria.

2. ZMBH - Zentrum für Molekulare Biologie der Universität Heidelberg,Im Neuenheimer Feld 282, 69120 Heidelberg, Germany.

Abstract

Polycomb/Trithorax group response elements (PRE/TREs) are fascinating chromosomal pieces. Just a few hundred base pairs long, these elements can remember and maintain the active or silent transcriptional state of their associated genes for many cell generations, long after the initial determining activators and repressors have disappeared. Recently, substantial progress has been made towards understanding the nuts and bolts of PRE/TRE function at the molecular level and in experimentally mapping PRE/TRE sites across whole genomes. Here we examine the insights, controversies and new questions that have been generated by this recent flood of data.

Publisher

The Company of Biologists

Subject

Developmental Biology,Molecular Biology

Link

http://journals.biologists.com/dev/article-pdf/134/2/223/1527079/223.pdf

Reference121 articles.

1. Ahmad, K. and Henikoff, S. (2002). The histone variant H3.3 marks active chromatin by replication-independent nucleosome assembly. Mol. Cell9,1191-1200.

2. Akasaka, T., Tsuji, K., Kawahira, H., Kanno, M., Harigaya, K.,Hu, L., Ebihara, Y., Nakahata, T., Tetsu, O., Taniguchi, M. et al.(1997). The role of mel-18, a mammalian Polycomb group gene,during IL-7-dependent proliferation of lymphocyte precursors. Immunity7,135-146.

3. Bantignies, F. and Cavalli, G. (2006). Cellular memory and dynamic regulation of polycomb group proteins. Curr. Opin. Cell Biol.18,275-283.

4. Bejarano, F. and Busturia, A. (2004). Function of the Trithorax-like gene during Drosophila development. Dev. Biol.268,327-341.

5. Bender, W. and Fitzgerald, D. P. (2002). Transcription activates repressed domains in the Drosophila bithorax complex. Development129,4923-4930.

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