Enabling neighbour labelling: using synthetic biology to explore how cells influence their neighbours-Reference-Cited by-同舟云学术

Enabling neighbour labelling: using synthetic biology to explore how cells influence their neighbours

Published:2024-01-01 Issue:1 Volume:151 Page:
ISSN:0950-1991
Container-title:Development
language:en
Short-container-title:

Author:

Malaguti Mattias¹^ORCID,Lebek Tamina¹^ORCID,Blin Guillaume¹^ORCID,Lowell Sally¹^ORCID

Affiliation:

1. Centre for Regenerative Medicine, Institute for Stem Cell Research, School of Biological Sciences, University of Edinburgh , 5 Little France Drive, Edinburgh EH16 4UU , UK

Abstract

ABSTRACT Cell-cell interactions are central to development, but exploring how a change in any given cell relates to changes in the neighbour of that cell can be technically challenging. Here, we review recent developments in synthetic biology and image analysis that are helping overcome this problem. We highlight the opportunities presented by these advances and discuss opportunities and limitations in applying them to developmental model systems.

Funder

Biotechnology and Biological Sciences Research Council

University of Edinburgh

Wellcome Trust

Publisher

The Company of Biologists

Subject

Developmental Biology,Molecular Biology

Link

https://journals.biologists.com/dev/article-pdf/doi/10.1242/dev.201955/3343542/dev201955.pdf

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