The developmental origins of adipose tissue-Reference-Cited by-同舟云学术

The developmental origins of adipose tissue

Published:2013-10-01 Issue:19 Volume:140 Page:3939-3949
ISSN:1477-9129
Container-title:Development
language:en
Short-container-title:

Author:

Berry Daniel C.¹,Stenesen Drew¹,Zeve Daniel¹,Graff Jonathan M.¹²

Affiliation:

1. Department of Developmental Biology, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.

2. Department of Molecular Biology, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.

Abstract

Adipose tissue is formed at stereotypic times and locations in a diverse array of organisms. Once formed, the tissue is dynamic, responding to homeostatic and external cues and capable of a 15-fold expansion. The formation and maintenance of adipose tissue is essential to many biological processes and when perturbed leads to significant diseases. Despite this basic and clinical significance, understanding of the developmental biology of adipose tissue has languished. In this Review, we highlight recent efforts to unveil adipose developmental cues, adipose stem cell biology and the regulators of adipose tissue homeostasis and dynamism.

Publisher

The Company of Biologists

Subject

Developmental Biology,Molecular Biology

Link

http://journals.biologists.com/dev/article-pdf/140/19/3939/1160391/3939.pdf

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