Pesticide Exposure as a Risk Factor for Parkinson's Disease

Author:

Saad Fatima Ez-Zahraa1,Lelo Aaron Pambu2ORCID,Smimih Kamal3,El-Mansoury Bilal1,lkhanouchi Manal4,El Amine Souad4,Bitar Abdelali1

Affiliation:

1. Faculty of Scienes, Universiy Chouaib Doukkali, Morocco

2. Kinchasa University, DRC

3. Faculty of Sciences and Techniques, Sultan Moulay Slimane University, Morocco

4. Independent Researcher, Morocco

Abstract

Pesticides are very unique environmental pollutants that are introduced into the environment specifically to fight pests, frequently by killing them, and to protect cultures against losses and vector-transmitted diseases. Many studies have found potential toxic effects of pesticides on many organisms such as humans. Neurotoxicity has been found to be associated with the use of certain classes of pesticides, including insecticides, herbicides, and fungicides. Observational research has shown an association between some pesticide exposure, such as Rotenone, Paraquat, Organochlorines, Organophosphates, Pyrethroids, and Triazines, and the etiology of Parkinson's disease. In this chapter, the authors discuss the mechanisms of action of different pesticides involved in the pathology of PD.

Publisher

IGI Global

Reference80 articles.

1. Agency Toxic Subst. Dis. Registry (ATSDR). (2005). Toxicological profile for alpha-, beta-, gamma-, and deltahexachlorocyclohexane. US Dep. Health Hum. Serv. https://www.atsdr.cdc.gov/toxprofiles/tp43-p.pdf

2. Parkinson’s disease and pesticides: A meta-analysis of disease connection and genetic alterations

3. Paraoxonase 1 Met–Leu 54 polymorphism is associated with Parkinson’s disease

4. Molecular Aspects of Dopaminergic Neurodegeneration: Gene-Environment Interaction in Parkin Dysfunction

5. Parkinson’s disease and pesticides: Are microRNAs the missing link?;A.Athina-Maria;The Science of the Total Environment,2020

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3