Computer Simulation Studies of Non-Thermal Plasma in Cancer Treatment-Reference-Cited by-同舟云学术

Computer Simulation Studies of Non-Thermal Plasma in Cancer Treatment

Published:2024-02-23 Issue: Volume: Page:97-112
ISSN:2327-5448
Container-title:Emerging Applications of Plasma Science in Allied Technologies
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Author:

Abduvokhidov Davronjon¹,Chen Zhitong²,Razzokov Jamoliddin³^ORCID

Affiliation:

1. R&D Center, New Uzbekistan University, Uzbekistan & Department of Information Technologies, Tashkent International University of Education, Uzbekistan & Institute of Material Sciences, Academy of Sciences, Uzbekistan

2. Institute of Biomedical and Health Engineering, Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences, China & Center for Advanced Therapy, National Innovation Center for Advanced Medical Devices, China

3. Institute of Fundamental and Applied Research, National Research University TIIAME, Uzbekistan & School of Engineering, Central Asian University, Uzbekistan & Department of Biomedical Engineering, Tashkent State Technical University, Uzbekistan

Abstract

Non-thermal plasma (NTP), the fourth state of matter, holds promise in altering biological matter, particularly in cancer treatment. NTP influences cell signaling by modifying key components, such as membranes, proteins, and DNA. It selectively targets cancer cells through the generation of reactive oxygen and nitrogen species (RONS), which modify amino acids within proteins. Understanding these molecular mechanisms is vital for optimizing NTP's potential in oncology. This book chapter reviews recent computer simulations and experimental findings exploring NTP's impact on proteins in cancer therapy, providing insights into how protein modifications affect cancer cell behavior and therapy responses. This knowledge advances NTP-based cancer treatments, offering the potential for personalized and targeted therapies in the future.

Publisher

IGI Global

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