Affiliation:
1. Tver State Medical University
2. G.N. Gabrichevskogo Moscow research institute for epidemiology and microbiology; Russian academy of post-graduate education Federal Research and Clinical Center of Specialized Medical Care and Medical Technologies FMBA of Russia
Abstract
The work characterizes the intestinal microbiota of patients with ischemic stroke, including the spectrum, frequency and number of microorganisms, as well as the spectrum and amount of gas signaling molecules secreted by lactobacilli. It was found that in patients with ischemic stroke, the frequency of the main representatives of normal microflora, Bifidobacterium spp., Lactobacillus spp., Escherichia coli, decreased in 2-3 times, and the same time the prevalence of Clostridia spp., Bacillus spp., Peptostreptococcus spp., Klebsiella spp. increased in 2-3 times; yeast like fungi C. albicans was isolated in 25% of cases. Lactobacilli isolated from the intestinal microbiota of patients with ischemic stroke were represented by a wide variety of species: L. rhamnosus, L. fermentum, L. plantarum, L. brevis, L. pentosus, L. curvatus, L. salivarius. In most cases, they did not produce NO, they released CO 2 times less compared to healthy people. The most active NO producers - L. plantarum, CO - L. rhamnosus.
Subject
Biochemistry (medical),Medical Laboratory Technology,General Medicine
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