Unleashing light's healing power: an overview of photobiomodulation for Alzheimer's treatment

Author:

Ramanishankar Aakash1,S Ankul Singh2ORCID,Begum Rukaiah F2ORCID,Jayasankar Narayanan2ORCID,Nayeem Afreen3ORCID,Prajapati Bhupendra G4ORCID,Nirenjen Shanmugasundaram2ORCID

Affiliation:

1. Department of Pharmacy Practice, School of Pharmaceutical Sciences, Vels Institute of Science Technology & Advanced Studies, Pallavaram, Chennai. India

2. Department of Pharmacology, SRM College of Pharmacy, SRM Institute of science & technology, Chennai, Tamil Nadu, India

3. Department of Pharmaceutics, Anand College of Pharmacy Agra-Delhi Highway (NH2) Keetham, Agra, Uttar Pradesh, 282007, India

4. Department of Pharmaceutics, Shree SK Patel College of Pharmaceutical Education & Research, Ganpat University, Kherva, 384012, India

Abstract

Aim: Photobiomodulation involves the use of low-level light therapy or near-infrared light therapy found to be useful in the treatment of a wide range of neurological diseases. Objective: The aim is to review the mechanism and clinical applications of photobiomodulation therapy (PBMT) in managing Alzheimer's disease. Methods: To ensure that the consensus statement accurately reflects both the experts' viewpoint and the most recent developments in the field, the expert opinions were recorded and thoroughly reviewed. Results: PBMT elicits reduction of beta-amyloid plaque, restoration of mitochondrial function, anti-inflammatory and antioxidant properties with a stimulation in ATP synthesis. Conclusion: The PBMT could be helpful in patients non-responsive to traditional pharmacological therapy providing significant aid in the management of Alzheimer's disease when introduced into the medical field.

Publisher

Future Science Ltd

Subject

Biotechnology

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