Migrasomes and tetraspanins in hepatocellular carcinoma: current status and future prospects

Author:

Zhang Zhongqi12ORCID,Zhang Tianmiao12,Zhang Rongcheng12,Zhang Zhengbao12,Tan Shengkui12

Affiliation:

1. Guangxi Key Laboratory of Environmental Exposomics & Entire Lifecycle Health, Guilin Medical University, Guilin, 541004, Guangxi, China

2. Department of Epidemiology & Health Statistics, Guilin Medical University, Guilin, 541004, Guangxi, China

Abstract

In recent years, many studies have attempted to clarify the formation, structure and biological function of migrasomes, which are defined as specialized organelles formed by the tips and intersections of Retraction Fibrils during cell migration. It has confirmed that migrasomes were involved in various critical biological processes and diseases, and has became a new research hotspot. In this paper, we reviewed the formation and biological functions of migrasomes, explored the relationship between migrasomes, tetraspanins and hepatocellular carcinoma and discussed the potential applications of migrasomes in hepatocellular carcinoma.

Funder

National Natural Science Foundation of China

Publisher

Future Science Ltd

Subject

Biotechnology

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