Molecularly imprinted polymers in biological applications

Author:

El-Schich Zahra1ORCID,Zhang Yuecheng12,Feith Marek13ORCID,Beyer Sarah12,Sternbæk Louise124,Ohlsson Lars12,Stollenwerk Maria12,Wingren Anette Gjörloff12ORCID

Affiliation:

1. Department of Biomedical Sciences, Faculty of Health & Society, Malmö University, Malmö, Sweden

2. Biofilms-Research Center for Biointerfaces, Malmö University, Malmö, Sweden

3. Department of Physiology, Faculty of Medicine, Masaryk University, Brno, Czech Republic

4. Phase Holographic Imaging AB, Lund, Sweden

Abstract

Molecularly imprinted polymers (MIPs) are currently widely used and further developed for biological applications. The MIP synthesis procedure is a key process, and a wide variety of protocols exist. The templates that are used for imprinting vary from the smallest glycosylated glycan structures or even amino acids to whole proteins or bacteria. The low cost, quick preparation, stability and reproducibility have been highlighted as advantages of MIPs. The biological applications utilizing MIPs discussed here include enzyme-linked assays, sensors, in vivo applications, drug delivery, cancer diagnostics and more. Indeed, there are numerous examples of how MIPs can be used as recognition elements similar to natural antibodies.

Funder

Biofilms Research Center for Biointerfaces

Horizon 2020 Framework Programme

Knowledge Foundation

Malmö University

Allmänna Sjukhusets i Malmö Stiftelse för Bekämpande av Cancer

Publisher

Future Science Ltd

Subject

General Biochemistry, Genetics and Molecular Biology,Biotechnology

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