Antibody Drug Conjugates: Application of Quantitative Pharmacology in Modality Design and Target Selection
Author:
Publisher
Springer Science and Business Media LLC
Subject
Pharmaceutical Science
Link
http://link.springer.com/content/pdf/10.1208/s12248-015-9766-0.pdf
Reference65 articles.
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2. Adair JR et al. Antibody-drug conjugates-a perfect synergy. Expert Opin Biol Ther. 2012;12(9):1191–206.
3. Perez HL et al. Antibody-drug conjugates: current status and future directions. Drug Discov Today. 2014;19(7):869–81.
4. Junutula JR et al. Site-specific conjugation of a cytotoxic drug to an antibody improves the therapeutic index. Nat Biotechnol. 2008;26(8):925–32.
5. McDonagh CF et al. Engineered anti-CD70 antibody-drug conjugate with increased therapeutic index. Mol Cancer Ther. 2008;7(9):2913–23.
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