Selection and Qualification of Simplified QSP Models When Using Model Order Reduction Techniques
Author:
Publisher
Springer Science and Business Media LLC
Subject
Pharmaceutical Science
Link
http://link.springer.com/article/10.1208/s12248-017-0170-9/fulltext.html
Reference29 articles.
1. van der Graaf PH, Benson N. Systems pharmacology: bridging systems biology and pharmacokinetics-pharmacodynamics (PKPD) in drug discovery and development. Pharm Res. 2011;28(7):1460–4. https://doi.org/10.1007/s11095-011-0467-9 .
2. Benson N, Matsuura T, Smirnov S, Demin O, Jones HM, Dua P, et al. Systems pharmacology of the nerve growth factor pathway: use of a systems biology model for the identification of key drug targets using sensitivity analysis and the integration of physiology and pharmacology. Interface Focus. 2013;3(2):20120071. https://doi.org/10.1098/rsfs.2012.0071 .
3. Jamei M. Recent advances in development and application of physiologically-based pharmacokinetic (PBPK) models: a transition from academic curiosity to regulatory acceptance. Curr Pharmacol Rep. 2016;2(3):161–9. https://doi.org/10.1007/s40495-016-0059-9 .
4. Peterson MC, Riggs MMFDA. Advisory meeting clinical pharmacology review utilizes a quantitative systems pharmacology (QSP) model: a watershed moment? CPT Pharmacometrics Syst Pharmacol. 2015;4(3):e00020. https://doi.org/10.1002/psp4.20 .
5. Tsamandouras N, Rostami-Hodjegan A, Aarons L. Combining the ‘bottom up’ and ‘top down’ approaches in pharmacokinetic modelling: fitting PBPK models to observed clinical data. Br J Clin Pharmacol. 2015;79(1):48–55. https://doi.org/10.1111/bcp.12234 .
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