Activin Type II Receptor Blockade for Treatment of Muscle Depletion in Chronic Obstructive Pulmonary Disease. A Randomized Trial

Author:

Polkey Michael I.1,Praestgaard Jens2,Berwick Amy3,Franssen Frits M. E.4,Singh Dave5,Steiner Michael C.6,Casaburi Richard7,Tillmann Hanns-Christian8,Lach-Trifilieff Estelle8,Roubenoff Ronenn8,Rooks Daniel S.3

Affiliation:

1. National Institute for Health Research Respiratory Biomedical Research Unit, Royal Brompton and Harefield National Health Service Foundation Trust and Imperial College London, London, United Kingdom

2. Novartis Pharmaceuticals Corporation, East Hanover, New Jersey

3. Novartis Institutes for BioMedical Research, Cambridge, Massachusetts

4. Department of Research and Education, CIRO, Center of Expertise for Chronic Organ Failure, Horn, the Netherlands

5. Centre for Respiratory Medicine and Allergy, University of Manchester and the Medicines Evaluation Unit, University Hospital of South Manchester National Health Service Foundation Trust, Manchester, United Kingdom

6. Centre for Exercise and Rehabilitation Science, National Institute for Health Research Leicester Biomedical Research Centre, Respiratory, Glenfield Hospital, Leicester, United Kingdom

7. Rehabilitation Clinical Trials Center, Los Angeles Biomedical Research Institute, Harbor-University of California Los Angeles Medical Center, Torrance, California; and

8. Novartis Institutes for BioMedical Research, Basel, Switzerland

Publisher

American Thoracic Society

Subject

Critical Care and Intensive Care Medicine,Pulmonary and Respiratory Medicine

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