Clonal Somatic Mutations in Chronic Lung Diseases Are Associated with Reduced Lung Function

Author:

Yun Jeong H.123ORCID,Khan M. A. Wasay4,Ghosh Auyon5ORCID,Hobbs Brian D.123ORCID,Castaldi Peter J.13,Hersh Craig P.123ORCID,Miller Peter G.36,Cool Carlyne D.7,Sciurba Frank8,Barwick Lucas9,Limper Andrew H.10,Flaherty Kevin11,Criner Gerard J.12,Brown Kevin13,Wise Robert14ORCID,Martinez Fernando15,Silverman Edwin K.13,DeMeo Dawn13,Cho Michael H.123ORCID,Bick Alexander G.4,

Affiliation:

1. Channing Division of Network Medicine and

2. Division of Pulmonary and Critical Care Medicine, Department of Medicine, Brigham and Women’s Hospital, Boston, Massachusetts;

3. Harvard Medical School, Boston, Massachusetts;

4. Division of Genetic Medicine, Department of Medicine, Vanderbilt University, Nashville, Tennessee;

5. Pulmonary Critical Care and Sleep Medicine, Upstate Medical University, Syracuse, New York;

6. Center for Cancer Research, Massachusetts General Hospital, Boston, Massachusetts;

7. Division of Pathology, Department of Medicine, University of Colorado, Aurora, Colorado;

8. Division of Pulmonary, Allergy and Critical Care Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania;

9. Emmes, Frederick, Maryland;

10. Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Mayo Clinic, Rochester, Minnesota;

11. Division of Pulmonary and Critical Care Medicine, University of Michigan Health System, Ann Arbor, Michigan;

12. Thoracic Medicine and Surgery, Lewis Katz School of Medicine at Temple University, Philadelphia, Pennsylvania;

13. Department of Medicine, National Jewish Health, Denver, Colorado;

14. Department of Medicine, Johns Hopkins Medicine, Baltimore, Maryland; and

15. Department of Medicine, Weill Cornell Medical College, New York, New York

Funder

National Heart, Lung, and Blood Institute

Harvard Medical School

National Institute on Aging

Burroughs Wellcome Fund

Pew Charitable Trusts

Alexander and Margaret Stewart Trust

Publisher

American Thoracic Society

Subject

Critical Care and Intensive Care Medicine,Pulmonary and Respiratory Medicine

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