Investigation of the Effect of Actinidia Deliciosa Kiwi Fruit Extracts on the Hematological and Biochemical Blood Parameters of Swiss Male

Abstract

Abstract The kiwi fruit is renowned for its high quantities of minerals, antioxidants, and vitamins as well as for its nutritional worth. The therapeutic qualities of kiwi fruit extract, such as its anti-tumor actions, anti-inflammatory, and antioxidants, have been used in food and medicine. However, further research is required to fully understand the chemical composition and potential health advantages of kiwi fruit extracts. This study extracted kiwi fruit peelings and core into aqueous and alcoholic solutions using conventional and ultrasound-assisted techniques The effects of the extracts on liver enzymes, kidney functions, and blood lipid proteins in Swiss male albino mice was also investigated in a laboratory animal experiment. The findings imply potential advantages for lowering the risk of atherosclerosis and cardiovascular diseases as the treatment with KPa20 from ultrasound-treated kiwi peels produced superior outcomes with reduced enzyme LDL and VLDL levels compared to the control group. The ALT and AST enzyme levels were not significantly changed by kiwi fruit extracts, indicating no negative effects. In the therapy group, the enzyme levels for ALT and AST were (39.20, 36.40) and (33.50, 32.33) international units per litre, respectively. While normal extracts (WP, KC, and KP) had slightly lower urea levels than those given extracts exposed to ultrasonic waves (WPa20, KCa20, and KPa20), the latter were slightly higher. Creatinine levels in the blood were not considerably impacted. The values for the treatment groups’ creatinine were 0.87 (WP), 0.83 (KCa20), 0.90 (KPa20), and 0.93 (KP). The study explored the health benefits of kiwi fruit peels and cores, revealing that Ultrasound technology was used to extract active chemicals, including phenolic compounds. Results showed increased extraction and antioxidant activity in extracts. Both regular and ultrasound-exposed kiwi fruit extracts showed therapeutic effects, decreasing triglyceride levels, total cholesterol, and lipoprotein levels.