Oxygen vacancy boosting Fenton reaction in bone scaffold towards fighting bacterial infection

Author:

Shuai CijunORCID,Shi Xiaoxin,Yang Feng,Tian Haifeng,Feng PeiORCID

Abstract

Highlights High-energy ball milling was proposed to construct oxygen vacancy defects. Scaffold with individualized shape and porous structure was fabricated by selective laser sintering. Antibacterial material was used to adsorb H2O2 to the site of bacterial infection. The accumulated H2O2 could amplify the Fenton reaction efficiency to induce more ·OH. The scaffold possessed matched mechanical properties and good biocompatibility.

Funder

Guangdong Province Precision Manufacturing and Intelligent production education Integration Innovation Platform

Independent Exploration and Innovation Project of Central South University

The Natural Science Foundation of China

Hunan Provincial Natural Science Foundation of China

The Project of State Key Laboratory of Precision Manufacturing for Extreme Service Performance

Technology Innovation Platform Project of Shenzhen Institute of Information Technology 2020

Jiangxi Provincial Natural Science Foundation of China

Publisher

IOP Publishing

Subject

Industrial and Manufacturing Engineering

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