Oncogenic dependency plays a dominant role in the immune response to cancer
Author:
Affiliation:
1. Department of Pathology, Stony Brook University, Stony Brook, NY 11794
2. Department of Molecular Genetics and Microbiology, Stony Brook University, Stony Brook, NY 11794
Abstract
Funder
HHS | NIH | National Cancer Institute
Publisher
Proceedings of the National Academy of Sciences
Subject
Multidisciplinary
Link
https://pnas.org/doi/pdf/10.1073/pnas.2308635120
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1. The clinical KRAS(G12C) inhibitor AMG 510 drives anti-tumour immunity
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3. Anti-tumor efficacy of a potent and selective non-covalent KRASG12D inhibitor
4. Discovery, Preclinical Characterization, and Early Clinical Activity of JDQ443, a Structurally Novel, Potent, and Selective Covalent Oral Inhibitor of KRASG12C
5. Therapeutic KRAS G12C inhibition drives effective interferon-mediated antitumor immunity in immunogenic lung cancers
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