Inhibition of helicase activity by a small molecule impairs Werner syndrome helicase (WRN) function in the cellular response to DNA damage or replication stress
Author:
Publisher
Proceedings of the National Academy of Sciences
Subject
Multidisciplinary
Reference28 articles.
1. DNA repair pathways as targets for cancer therapy
2. Helicases as Prospective Targets for Anti-Cancer Therapy
3. Mechanisms of RecQ helicases in pathways of DNA metabolism and maintenance of genomic stability
4. RecQ helicases: multifunctional genome caretakers
5. Werner and Hutchinson–Gilford progeria syndromes: mechanistic basis of human progeroid diseases
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