Mnk earmarks eIF4E for cancer therapy
Author:
Affiliation:
1. Department of Biochemistry and Molecular Genetics, University of Illinois, Chicago, IL 60607
Publisher
Proceedings of the National Academy of Sciences
Link
https://pnas.org/doi/pdf/10.1073/pnas.1008908107
Reference13 articles.
1. The Two TORCs and Akt
2. eIF4E phosphorylation promotes tumorigenesis and is associated with prostate cancer progression
3. Combined deficiency for MAP kinase-interacting kinase 1 and 2 (Mnk1 and Mnk2) delays tumor development
4. Akt deficiency impairs normal cell proliferation and suppresses oncogenesis in a p53-independent and mTORC1-dependent manner
5. eIF4E, the mRNA cap-binding protein: from basic discovery to translational researchThis paper is one of a selection of papers published in this Special Issue, entitled CSBMCB — Systems and Chemical Biology, and has undergone the Journal's usual peer review process.
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