Two distinct pathways of positive selection for thymocytes
Author:
Publisher
Proceedings of the National Academy of Sciences
Subject
Multidisciplinary
Reference31 articles.
1. CD4 expressed on earliest T-lineage precursor cells in the adult murine thymus
2. Intrathymically expressed c-kit ligand (stem cell factor) is a major factor driving expansion of very immature thymocytes in vivo
3. T cell receptor-mediated negative selection of autoreactive T lymphocyte precursors occurs after commitment to the CD4 or CD8 lineages.
4. The kinetics of T cell antigen receptor expression by subgroups of CD4+8+ thymocytes: delineation of CD4+8+3(2+) thymocytes as post-selection intermediates leading to mature T cells.
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