Role of decay-accelerating factor in regulating complement activation on the erythrocyte surface as revealed by gene targeting
Author:
Publisher
Proceedings of the National Academy of Sciences
Subject
Multidisciplinary
Reference35 articles.
1. Inhibition of complement activation on the surface of cells after incorporation of decay-accelerating factor (DAF) into their membranes.
2. The mechanism of action of decay-accelerating factor (DAF). DAF inhibits the assembly of C3 convertases by dissociating C2a and Bb.
3. Affected erythrocytes of patients with paroxysmal nocturnal hemoglobinuria are deficient in the complement regulatory protein, decay accelerating factor.
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