AF5q31, a newly identified AF4-related gene, is fused to MLL in infant acute lymphoblastic leukemia with ins(5;11)(q31;q13q23)
Author:
Publisher
Proceedings of the National Academy of Sciences
Subject
Multidisciplinary
Reference41 articles.
1. Cloning of cDNAs of the MLL gene that detect DNA rearrangements and altered RNA transcripts in human leukemic cells with 11q23 translocations.
2. Involvement of a homolog of Drosophila trithorax by 11q23 chromosomal translocations in acute leukemias
3. The t(4;11) chromosome translocation of human acute leukemias fuses the ALL-1 gene, related to Drosophila trithorax, to the AF-4 gene
4. A trithorax–like gene is interrupted by chromosome 11q23 translocations in acute leukaemias
5. MLL, a mammalian trithorax-group gene, functions as a transcriptional maintenance factor in morphogenesis
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