Insights into the serine protease mechanism from atomic resolution structures of trypsin reaction intermediates
Author:
Publisher
Proceedings of the National Academy of Sciences
Subject
Multidisciplinary
Reference45 articles.
1. Nitrogen-15 NMR spectroscopy of hydrogen-bonding interactions in the active site of serine proteases: evidence for a moving histidine mechanism
2. Unusual 1H NMR chemical shifts support (His) Cepsilon 1---H{middle dot}{middle dot}{middle dot}O==C H-bond: Proposal for reaction-driven ring flip mechanism in serine protease catalysis
3. Serine Protease Mechanism and Specificity
4. Theoretical Studies on the Deacylation Step of Serine Protease Catalysis in the Gas Phase, in Solution, and in Elastase
5. Molecular dynamics simulations of the acyl-enzyme and the tetrahedral intermediate in the deacylation step of serine proteases
Cited by 125 articles. 订阅此论文施引文献 订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献
1. Crystal structure of the Michaelis complex of trypsin with N‐α‐benzoyl‐l‐arginine ethyl ester;Journal of the Chinese Chemical Society;2024-09-02
2. Computational design of serine hydrolases;2024-08-30
3. Orthoflaviviral Inhibitors in Clinical Trials, Preclinical In Vivo Efficacy Targeting NS2B-NS3 and Cellular Antiviral Activity via Competitive Protease Inhibition;Molecules;2024-08-27
4. Biomolecular Condensation of Trypsin Prevents Autolysis and Promotes Ca2+-Mediated Activation of Esterase Activity;Biomacromolecules;2024-08-08
5. An integrated multitool analysis contributes elements to interpreting unclassified factor IX missense variants associated with hemophilia B;Journal of Thrombosis and Haemostasis;2024-07
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线，采集、加工和组织学术论文而形成的新型学术文献查询和分析系统，可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容，当前同舟云学术共收录了国内外主流学术期刊6万余种，收集的期刊论文及会议论文总量共计约1.5亿篇，并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询！咨询电话：010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3