1. a follow-up of that cohort to determine if antiestrogen in the classical sense of block
2. functional developmental toxicity is pre- ing estrogen binding to the estrogen recep
3. sent. In contrast clear evidence of develop- tor. It may alter the metabolism of
4. mental toxicity has been found in two estrogen potentially leading to a decrease
5. cohorts inadvertently exposed to complex in the active form of the hormone at target