A Chemical Category-Based Prioritization Approach for Selecting 75 Per- and Polyfluoroalkyl Substances (PFAS) for Tiered Toxicity and Toxicokinetic Testing-Reference-Cited by-同舟云学术

A Chemical Category-Based Prioritization Approach for Selecting 75 Per- and Polyfluoroalkyl Substances (PFAS) for Tiered Toxicity and Toxicokinetic Testing

Published:2019-01 Issue:1 Volume:127 Page:014501
ISSN:0091-6765
Container-title:Environmental Health Perspectives
language:en
Short-container-title:Environ Health Perspect

Author:

Patlewicz Grace¹,Richard Ann M.¹,Williams Antony J.¹,Grulke Christopher M.¹,Sams Reeder¹,Lambert Jason²,Noyes Pamela D.³,DeVito Michael J.⁴,Hines Ronald N.⁵,Strynar Mark⁶,Guiseppi-Elie Annette⁶,Thomas Russell S.¹

Affiliation:

1. National Center for Computational Toxicology, Office of Research and Development (ORD), U.S. Environmental Protection Agency (EPA), Research Triangle Park, North Carolina, USA

2. National Center for Environmental Assessment (NCEA), ORD, U.S. EPA, Cincinnati, Ohio, USA

3. Integrated Risk Information System Division, NCEA, ORD, U.S. EPA, Washington, District of Columbia, USA

4. National Toxicology Program, National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services, Research Triangle Park, North Carolina, USA

5. National Health and Environmental Effects Research Laboratory, ORD, U.S. EPA, Research Triangle Park, North Carolina, USA

6. National Exposure Research Laboratory, ORD, U.S. EPA, Research Triangle Park, North Carolina, USA

Publisher

Environmental Health Perspectives

Subject

Health, Toxicology and Mutagenesis,Public Health, Environmental and Occupational Health

Reference14 articles.

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2. In Vitro Screening of Environmental Chemicals for Targeted Testing Prioritization: The ToxCast Project

3. Integrated Model of Chemical Perturbations of a Biological Pathway Using 18In VitroHigh-Throughput Screening Assays for the Estrogen Receptor

4. Development and Validation of a Computational Model for Androgen Receptor Activity

5. Use of category approaches, read-across and (Q)SAR: General considerations

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