Mutants ofAspergillus nidulansunable to use choline-0-sulphate

Abstract

SUMMARYMutants ofAspergillus nidulansunable to use either the choline moiety or the sulphate moiety of exogenous choline-0-sulphate have been selected. Choline-0-sulphate non-utilizing (csu) mutations have no other apparent pleiotropic effects, but it has not yet been established whether they lead to loss of choline sulphatase (and thus of the ability to utilize endogenously produced choline-0-sulphate) or to loss of a specific transport system for choline-0-sulphate or to loss of both.