Author:
KELLY H. A.,SIEBERT D.,HAMMOND R.,LEYDON J.,KIELY P.,MASKILL W.
Abstract
The age-specific immunity to human parvovirus infection was estimated in Victoria, Australia
using prospectively collected samples from the Royal Children's Hospital, the Royal Women's
Hospital and the Australian Red Cross Blood Service and from sera stored at the Victorian
Infectious Diseases Reference Laboratory (VIDRL). All testing was performed at VIDRL using
a commercial enzyme-linked immunosorbent assay (Biotrin). Of the 824 sera tested, 28% of
those drawn from people aged 0–9 years contained protective antibodies to human parvovirus.
This rose to 51% in the next decade of life. There was then a slow rise to about 78%
immunity over 50 years of age. An analysis of all requests for parvovirus serology at VIDRL
from 1992 to 1998 suggested that parvovirus tended to occur in 4-year cycles, with 2 epidemic
years followed by 2 endemic years. A review of published reports of parvovirus immunity
suggested that parvovirus infection may be more common, with a correspondingly higher
proportion of the community immune, in temperate as opposed to tropical countries.
Publisher
Cambridge University Press (CUP)
Subject
Infectious Diseases,Epidemiology
Cited by
109 articles.
订阅此论文施引文献
订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献