A large A(H3N2) influenza outbreak with a high attack rate in a drug user community in Italy, April 2022

Author:

Gori MariaORCID,Fappani ClaraORCID,Bianchi SilviaORCID,Canuti MartaORCID,Colzani DanielaORCID,Ottogalli Paolo,Duehren Sarah,Tanzi ElisabettaORCID,Amendola AntonellaORCID,Boschini Antonio

Abstract

Abstract Despite the COVID-19 pandemic, influenza remains an important issue. Especially in community settings, influenza outbreaks can be difficult to control and can result in high attack rates. In April 2022, a large A(H3N2) influenza outbreak spread in the largest Italian drug-rehabilitation community. One hundred eighty-four individuals presented influenza-like symptoms (attack rate of 26.2%); 56% previously received the influenza vaccine. Sequence analyses highlighted a genetic drift from the vaccine strain, which may have caused the observed lack of protection.

Publisher

Cambridge University Press (CUP)

Subject

Infectious Diseases,Epidemiology

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