A study on Asymptomatic Bacteriuria in Women with Diabetes Mellitus

Abstract

Background: Diabetes is the common predisposing factor for Urinary Tract Infection. In diabetic patients, asymptomatic bacteriuria is more prevalent in females compared to male patients. Bacteria count for similar species over 10^5 per ml in urine specimen of mild stream clean catch without urinary infection is known as Asymptomatic bacteriuria (ASB). Asymptomatic bacteriuria appears to be incurable, recurring in diabetic patients. Aim: The current study aim to determine the outcomes of asymptomatic bacteriuria in patients with diabetes mellitus. Materials and Methods: This cross-sectional study was carried out on 85 women of diabetes mellitus in the department of General Medicine, Qazi Hussain Ahmad Medical Complex Nowshera and Jinnah Medical College Peshawar for duration of six months from June 2020 to December 2020. Detailed and follow-up histories of all the patients were studied, compared, and reported. Individuals who met the inclusive criteria were enrolled in this study. Women on steroid therapy, with immunodeficiency, and incomplete follow-up history were excluded. The outcome of symptomatic and asymptomatic patients was followed for positive culture in a time span of 3 and 6 months. SPSS version 20 was used for data analysis purposes. Results: The mean age of the patients was 57+15.3. Of the total, 13 (15.3%) UTI were symptomatic women with diabetes, and UTI in asymptomatic patients was 72 (84.7%). In symptomatic cases, the prevalence of hypertension, Macroalbuminuria, and Microalbuminuria were 7 (53.4%), 3 (23.3%), and 3 (23.3%) respectively. HbA1C and eGFR (ml/min/1.732) level was 8.5+0.85 and 92.07+10.3 respectively. Conclusion: Our study concluded that urinary culture detected significant bacteriuria without symptoms such as fever, painful micturition, and urgency, frequent micturition, flank pain, burning micturition, and suprapubic pain. Symptomatic and asymptomatic bacteriuria is more common in females. Also, asymptomatic bacteriuria appears to be incurable, recurring in diabetic females. Keywords: Asymptomatic, Bacteriuria, Diabetes mellitus