Clinicogenomic factors of biotherapy immunogenicity in autoimmune disease: A prospective multicohort study of the ABIRISK consortium

Author:

Hässler SigneORCID,Bachelet DelphineORCID,Duhaze JulianneORCID,Szely Natacha,Gleizes Aude,Hacein-Bey Abina Salima,Aktas OrhanORCID,Auer MichaelORCID,Avouac JerômeORCID,Birchler Mary,Bouhnik Yoram,Brocq Olivier,Buck-Martin Dorothea,Cadiot Guillaume,Carbonnel Franck,Chowers Yehuda,Comabella ManuelORCID,Derfuss Tobias,De Vries NiekORCID,Donnellan Naoimh,Doukani Abiba,Guger MichaelORCID,Hartung Hans-Peter,Kubala Havrdova EvaORCID,Hemmer Bernhard,Huizinga Tom,Ingenhoven Kathleen,Hyldgaard-Jensen Poul Erik,Jury Elizabeth C.ORCID,Khalil MichaelORCID,Kieseier Bernd,Laurén Anna,Lindberg RaijaORCID,Loercher AmyORCID,Maggi Enrico,Manson JessicaORCID,Mauri Claudia,Mohand Oumoussa Badreddine,Montalban Xavier,Nachury MariaORCID,Nytrova Petra,Richez Christophe,Ryner Malin,Sellebjerg Finn,Sievers Claudia,Sikkema Dan,Soubrier MartinORCID,Tourdot Sophie,Trang CarolineORCID,Vultaggio Alessandra,Warnke ClemensORCID,Spindeldreher SebastianORCID,Dönnes PierreORCID,Hickling Timothy P.,Hincelin Mery Agnès,Allez MatthieuORCID,Deisenhammer FlorianORCID,Fogdell-Hahn AnnaORCID,Mariette XavierORCID,Pallardy Marc,Broët PhilippeORCID,

Funder

Innovative Medicines Initiative

European Federation of Pharmaceutical Industries and Associations

Publisher

Public Library of Science (PLoS)

Subject

General Medicine

Reference59 articles.

1. Immunogenicity of Biopharmaceuticals

2. Assessment and Reporting of the Clinical Immunogenicity of Therapeutic Proteins and Peptides—Harmonized Terminology and Tactical Recommendations.;G Shankar;AAPS J,2014

3. Assessing the Immunogenicity of Biopharmaceuticals.;C Pineda;BioDrugs,2016

4. Standardizing terms, definitions and concepts for describing and interpreting unwanted immunogenicity of biopharmaceuticals: recommendations of the Innovative Medicines Initiative ABIRISK consortium: Immunogenicity of biopharmaceuticals: ABIRISK recommendations;B Rup;Clin Exp Immunol,2015

5. ABIRISK Consortium. ABIRISK: Anti-Biopharmaceutical Immunization: Prediction and Analysis of Clinical Relevance to Minimize the Risk [Internet]. 2018 [cited 2020 Jan 1]. Available from: https://www.imi.europa.eu/projects-results/project-factsheets/abiriskref:end

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