Safety, tolerability, and pharmacokinetics of AL-335 in healthy volunteers and hepatitis C virus-infected subjects

Author:

McClure Matthew W.,Berliba Elina,Tsertsvadze Tengiz,Streinu-Cercel Adrian,Vijgen Leen,Astruc Béatrice,Patat Alain,Westland Christopher,Chanda Sushmita,Zhang Qingling,Kakuda Thomas N.,Vuong Jennifer,Khorlin Nick,Beigelman Leonid,Blatt Lawrence M.,Fry JohnORCID

Funder

Alios BioPharma Inc., part of the Janssen Pharmaceutical Companies

Publisher

Public Library of Science (PLoS)

Subject

Multidisciplinary

Reference19 articles.

1. World Health Organization. Hepatitis C–Fact Sheet 164. 2017. Available from: http://www.who.int/mediacentre/factsheets/fs164/en/

2. EASL recommendations on treatment of hepatitis C 2016;J Hepatol,2017

3. American Association for the Study of Liver Diseases, Infectious Diseases Society of America. HCV guidance: recommendations for testing, managing and treating hepatitis C. 2017. Available from: https://www.hcvguidelines.org/

4. Impact of antiviral therapy on hepatocellular carcinoma and mortality in patients with chronic hepatitis C: systematic review and meta-analysis;CS Bang;BMC Gastroenterol,2017

5. Global epidemiology and burden of HCV infection and HCV-related disease;AP Thrift;Nat Rev Gastroenterol Hepatol,2017

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