Toward Understanding the Catalytic Mechanism of Human Paraoxonase 1: Site-Specific Mutagenesis at Position 192

Author:

Aggarwal Geetika,Prajapati Rameshwar,Tripathy Rajan K.,Bajaj Priyanka,Iyengar A. R. Satvik,Sangamwar Abhay T.,Pande Abhay H.

Publisher

Public Library of Science (PLoS)

Subject

Multidisciplinary

Reference46 articles.

1. Studies on human serum paraoxonase/aryl esterase;BN La Du;Chem Biol Interact,1993

2. Paraoxonase: biochemistry, genetics and relationship to plasma lipoproteins;MI Mackness;Curr Opin Lipidol,1996

3. Human serum paraoxonase (PON1) isozymes Q and R hydrolyze lactones and cyclic carbonate esters;S Billecke;Drug Metab Dispos,2000

4. Structure-reactivity studies of serum paraoxonase PON1 suggests that its native activity is lactonase;K Olga;Biochemistry,2005

5. Functional genomics of the paraoxonase (PON1) polymorphisms: effects on pesticide sensitivity, cardiovascular disease, and drug metabolism;LG Costa;Annu Rev Med,2003

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