Conjugation of Methotrexate-Amino Derivatives to Macromolecules through Carboxylate Moieties Is Superior Over Conventional Linkage to Amino Residues: Chemical, Cell-Free and In Vitro Characterizations
Author:
Funder
This work was supported by a Kimmelman grant from the Weizmann Institute
Publisher
Public Library of Science (PLoS)
Subject
Multidisciplinary
Reference23 articles.
1. New Technologies to Prolong Life-time of Peptide and Protein Drugs In vivo;Y Shechter;International Journal of Peptide Research and Therapeutics,2007
2. Establishing the principle of reversibility in peptide/protein and small-molecule therapy;Y Shechter;Ther Deliv,2012
3. New concept for long-acting insulin: spontaneous conversion of an inactive modified insulin to the active hormone in circulation: 9-fluorenylmethoxycarbonyl derivative of insulin;E Gershonov;Diabetes,1999
4. A novel approach for a water-soluble long-acting insulin prodrug: design, preparation, and analysis of [(2-sulfo)-9-fluorenylmethoxycarbonyl](3)-insulin;E Gershonov;J Med Chem,2000
5. Prolonging the half-life of human interferon-alpha 2 in circulation: Design, preparation, and analysis of (2-sulfo-9-fluorenylmethoxycarbonyl)7- interferon-alpha 2;Y Shechter;Proc Natl Acad Sci U S A,2001
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