Crystal Structures and Molecular Dynamics Simulations of Thermophilic Malate Dehydrogenase Reveal Critical Loop Motion for Co-Substrate Binding

Author:

Hung Chih-Hung,Hwang Tzann-Shun,Chang Yu-Yung,Luo Huei-Ru,Wu Szu-Pei,Hsu Chun-Hua

Publisher

Public Library of Science (PLoS)

Subject

Multidisciplinary

Reference37 articles.

1. Malate dehydrogenases--structure and function;P Minarik;Gen Physiol Biophys,2002

2. Malate dehydrogenase from thermophilic and mesophilic bacteria. Molecular size, subunit structure, amino acid composition, immunochemical homology, and catalytic activity;TK Sundaram;Biochemistry,1980

3. Physicochemical properties of pig and horse heart mitochondrial malate dehydrogenase;CJ Thorne;J Biol Chem,1963

4. Inhibition of the thioredoxin-dependent activation of the NADP-malate dehydrogenase and cofactor specificity;I Schepens;J Biol Chem,2000

5. Complete nucleotide sequence of the Escherichia coli gene encoding malate dehydrogenase;L McAlister-Henn;Nucleic Acids Res,1987

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