Association of ABCC2 −24C>T Polymorphism with High-Dose Methotrexate Plasma Concentrations and Toxicities in Childhood Acute Lymphoblastic Leukemia

Author:

Liu Yan,Yin You,Sheng Qi,Lu Xiaotong,Wang Fang,Lin Zhiyan,Tian Huaiping,Xu Ajing,Zhang Jian

Publisher

Public Library of Science (PLoS)

Subject

Multidisciplinary

Reference21 articles.

1. Treatment of acute lymphoblastic leukemia;CH Pui;N Engl J Med,2006

2. A new mechanism of methotrexate action revealed by target screening with affinity beads;H Uga;Mol Pharmacol,2006

3. Impact of ABCC2 polymorphisms on high-dose methotrexate pharmacokinetics in patients with lymphoid malignancy;N Simon;Pharmacogenomics J,2012

4. Intracellular disposition of methotrexate in acute lymphoblastic leukemia in children;TA de Beaumais;Curr Drug Metab,2012

5. Pharmacokinetically guided administration of chemotherapeutic agents;HJ Van Den Bongard;Clin Pharmacokinet,2000

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