siRNA Off-Target Effects Can Be Reduced at Concentrations That Match Their Individual Potency-Reference-Cited by-同舟云学术

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siRNA Off-Target Effects Can Be Reduced at Concentrations That Match Their Individual Potency

Published:2011-07-05 Issue:7 Volume:6 Page:e21503
ISSN:1932-6203
Container-title:PLoS ONE
language:en
Short-container-title:PLoS ONE

Author:

Caffrey Daniel R.,Zhao Juan,Song Zhili,Schaffer Michael E.,Haney Steven A.,Subramanian Romesh R.,Seymour Albert B.,Hughes Jason D.

Publisher

Public Library of Science (PLoS)

Subject

Multidisciplinary

Reference43 articles.

1. The art and design of genetic screens: RNA interference.;M Boutros;Nat Rev Genet,2008

2. RNAi therapeutics: principles, prospects and challenges.;L Aagaard;Adv Drug Deliv Rev,2007

3. Origins and Mechanisms of miRNAs and siRNAs.;RW Carthew;Cell,2009

4. In vitro reconstitution of the human RISC-loading complex.;IJ MacRae;Proc Natl Acad Sci U S A,2008

5. Role for a bidentate ribonuclease in the initiation step of RNA interference.;E Bernstein;Nature,2001

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