Culture density contributes to hepatic functions of fresh human hepatocytes isolated from chimeric mice with humanized livers: Novel, long-term, functional two-dimensional in vitro tool for developing new drugs
Author:
Funder
Japan Agency for Medical Research and Development
Publisher
Public Library of Science (PLoS)
Subject
Multidisciplinary
Reference66 articles.
1. In vitro evaluation of cytochrome P450 and glucuronidation activities in hepatocytes isolated from liver-humanized mice;C Yamasaki;Drug Metab Pharmacokinet,2010
2. Drug metabolizing capacity of cryopreserved human, rat, and mouse liver parenchymal cells in suspension;P Steinberg;Drug Metab Dispos,1999
3. Biochemical studies on liver functions in primary cultured hepatocytes of adult rats;K Tanaka;J Biochem,1978
4. Human adult hepatocytes in primary monolayer culture. Maintenance of mixed function oxidase and conjugation pathways of drug metabolism;MH Grant;Biochem Pharmacol,1987
5. Chimeric mice with humanized livers: a unique tool for in vivo and in vitro enzyme induction studies;M Kakuni;Int J Mol Sci,2013
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