Internal genes of a highly pathogenic H5N1 influenza virus determine high viral replication in myeloid cells and severe outcome of infection in mice

Author:

Li Hui,Bradley Konrad C.,Long Jason S.ORCID,Frise Rebecca,Ashcroft Jonathan W.ORCID,Hartgroves Lorian C.,Shelton HollyORCID,Makris SpyridonORCID,Johansson CeciliaORCID,Cao Bin,Barclay Wendy S.ORCID

Funder

Wellcome Trust

National Science Fund for Distinguished Young Scholars

Biotechnology and Biological Sciences Research Council

National Heart and Lung Institute

Rosetrees Trust

Publisher

Public Library of Science (PLoS)

Subject

Virology,Genetics,Molecular Biology,Immunology,Microbiology,Parasitology

Reference82 articles.

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2. Interferon-induced transmembrane protein-3 genetic variant rs12252-C is associated with severe influenza in Chinese individuals;YH Zhang,2013

3. Post-exposure treatment with whole inactivated H5N1 avian influenza virus protects against lethal homologous virus infection in mice;M Hagan,2016

4. Cellular immune correlates of protection against symptomatic pandemic influenza;S Sridhar,2013

5. Pathogenesis of the 1918 pandemic influenza virus;T Watanabe,2011

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