SARS-CoV-2 infection of African green monkeys results in mild respiratory disease discernible by PET/CT imaging and shedding of infectious virus from both respiratory and gastrointestinal tracts

Author:

Hartman Amy L.ORCID,Nambulli Sham,McMillen Cynthia M.ORCID,White Alexander G.,Tilston-Lunel Natasha LouiseORCID,Albe Joseph R.,Cottle EmilyORCID,Dunn Matthew D.ORCID,Frye L. James,Gilliland Theron H.,Olsen Emily L.ORCID,O’Malley Katherine J.,Schwarz Madeline M.,Tomko Jaime A.,Walker Reagan C.ORCID,Xia Mengying,Hartman Matthew S.,Klein Edwin,Scanga Charles A.ORCID,Flynn JoAnne L.ORCID,Klimstra William B.,McElroy Anita K.ORCID,Reed Douglas S.ORCID,Duprex W. Paul

Funder

Bill and Melinda Gates Foundation

Burroughs Wellcome Fund

National Institute of Allergy and Infectious Diseases

Publisher

Public Library of Science (PLoS)

Subject

Virology,Genetics,Molecular Biology,Immunology,Microbiology,Parasitology

Reference45 articles.

1. Establishment of an African green monkey model for COVID-19;C Woolsey;bioRxiv,2020

2. Respiratory disease in rhesus macaques inoculated with SARS-CoV-2;VJ Munster;Nature,2020

3. Comparative pathogenesis of COVID-19, MERS, and SARS in a nonhuman primate model;B Rockx;Science,2020

4. Infection with Novel Coronavirus (SARS-CoV-2) Causes Pneumonia in the Rhesus Macaques;C Shan;Research Square,2020

5. Simian Immunodeficiency Virus SIVagm.sab Infection of Caribbean African Green Monkeys: a New Model for the Study of SIV Pathogenesis in Natural Hosts;I Pandrea;Journal of Virology,2006

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