Pharmacotherapeutic Advances in Cardiac Resuscitation: A Review of the Advanced Cardiac Life Support (ACLS) 2000 Guidelines and Their Impact on Pharmacy Practice

Abstract

The treatment of sudden cardiac death is a challenging area of pharmacotherapy. Despite decades of medication use, outcomes from the treatment of cardiac arrest remain poor. Recent advances in the treatment of cardiac arrest have been incorporated into the American Heart Association’s Advanced Cardiac Life Support 2000 guidelines. A summary and review of these guidelines are presented. Included in the changes to the cardiac arrest treatment guidelines are new medications (amiodarone and vasopressin), new approaches to using medications and the evidence to support these changes. The implications of instituting these new guidelines and strategies for the implementation of the new paradigm are discussed.