Early intervention in pertussis outbreak with high attack rate in cohort of adolescents with complete acellular pertussis vaccination in Valencia, Spain, April to May 2015

Author:

Míguez Santiyán A1,Ferrer Estrems R2,Chover Lara J L1,Alberola Enguídanos J3,Nogueira Coito J M3,Salazar Cifre A1

Affiliation:

1. Epidemiology Department, Public Health Centre of Valencia (DGSP), Valencia, Spain

2. Preventive Medicine Department, Consorcio Hospital General Universitario de Valencia, Valencia, Spain

3. Microbiology Department, Hospital Universitario Dr. Peset, Valencia, Spain

Abstract

Forty-three pertussis cases reported in May 2015 in Valencia were linked to a school outbreak where 90% of the students had been vaccinated. Cases were diagnosed upon paediatrician consultation and in hospital emergency units. Approximately half of the cases were students born in 2002, the first age cohort with complete shift to acellular pertussis vaccine. Public health intervention, visiting school premises to conduct interviews, sample collection and early antibiotic prophylaxis stopped further spread in the community.

Publisher

European Centre for Disease Control and Prevention (ECDC)

Reference16 articles.

1. Generalitat Valenciana. Conselleria de Sanitat. Dirección General de Salud Pública. [General Directorate of Public Health]. Valencia: Generalitat Valenciana. [Accessed 9 Jul 2015]. Spanish. Available from: http://www.sp.san.gva.es

2. Centro Nacional de Epidemiología. Instituto de Salud Carlos III. Red Nacional de Vigilancia Epidemiológica. Protocolos de enfermedades de declaración obligatoria. [Protocol for diseases with mandatory notification]. Madrid, 2013. [Accessed 9 Jul 2015]. Spanish. Available from: http://www.isciii.es/ISCIII/es/contenidos/fd-servicios-cientifico-tecnicos/fd-vigilancias-alertas/PROTOCOLOS_RENAVE.pdf

3. World Health Organization (WHO). WHO SAGE pertussis working group. Background paper. SAGE April 2014. Geneva: WHO. [Accessed 9 Jul 2015]. Available from: http://www.who.int/immunization/sage/meetings/2014/april/1_Pertussis_background_FINAL4_web.pdf

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