Novel plasmid-mediated colistin resistance mcr-4 gene in Salmonella and Escherichia coli, Italy 2013, Spain and Belgium, 2015 to 2016

Author:

Carattoli Alessandra1,Villa Laura1,Feudi Claudia12,Curcio Ludovica3,Orsini Serenella3,Luppi Andrea4,Pezzotti Giovanni3,Magistrali Chiara Francesca3

Affiliation:

1. Department of Infectious Diseases, Istituto Superiore di Sanità, Rome, Italy

2. Institute of Microbiology and Epizootics, Centre for Infection Medicine, Department of Veterinary Medicine, Freie Universität Berlin, Berlin, Germany

3. Istituto Zooprofilattico Sperimentale dell'Umbria e delle Marche, Perugia, Italy

4. Istituto Zooprofilattico Sperimentale della Lombardia e dell’Emilia Romagna, Reggio Emilia, Italy

Abstract

A novel mcr colistin resistance gene was identified in a strain of Salmonella enterica, monophasic variant of serovar Typhimurium (4,5,12:i:- ), isolated from a pig at slaughter in Italy in 2013, and in Escherichia coli strains collected during routine diagnostic of post-weaning diarrhoea in pigs from Spain and Belgium in 2015 and 2016. Immediate implementation of mcr-screening including this novel gene variant is required for Salmonella and E. coli from humans and food-producing animals in Europe.

Publisher

European Centre for Disease Control and Prevention (ECDC)

Subject

Virology,Public Health, Environmental and Occupational Health,Epidemiology

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