Severe paediatric conditions linked with EV-A71 and EV-D68, France, May to October 2016

Author:

Antona Denise1,Kossorotoff Manoëlle2,Schuffenecker Isabelle3,Mirand Audrey4,Leruez-Ville Marianne5,Bassi Clément6,Aubart Mélodie2,Moulin Florence7,Lévy-Bruhl Daniel1,Henquell Cécile4,Lina Bruno3,Desguerre Isabelle2

Affiliation:

1. Direction des maladies infectieuses, Santé publique France, Saint-Maurice, France

2. Service de neuropédiatrie, AP-HP, Hôpital Necker – Enfants malades, Paris, France

3. CNR des entérovirus et parechovirus, laboratoire de virologie, Hospices civils de Lyon, Lyon, France

4. CNR des entérovirus et parechovirus-laboratoire associé, laboratoire de virologie, CHU de Clermont-Ferrand, Clermont Ferrand, France

5. Laboratoire de virologie, AP-HP, Hôpital Necker – Enfants malades, Paris, France

6. Cellule d’intervention en région Ile de France, Santé publique France, Paris, France

7. Service de réanimation pédiatrique, AP-HP, Hôpital Necker – Enfants malades, Paris, France

Abstract

We report 59 cases of severe paediatric conditions linked with enterovirus (EV)-A71 and EV-D68 in France between May and October 2016. Fifty-two children had severe neurological symptoms. EV sequence-based typing for 42 cases revealed EV-A71 in 21 (18 subgenotype C1, detected for the first time in France) and EV-D68 in eight. Clinicians should be encouraged to obtain stool and respiratory specimens from patients presenting with severe neurological disorders for EV detection and characterisation.

Publisher

European Centre for Disease Control and Prevention (ECDC)

Subject

Virology,Public Health, Environmental and Occupational Health,Epidemiology

Reference11 articles.

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